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Results for "

Maleic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Androgen Receptor (1) Bacterial (2) Biochemical Assay Reagents (7) Chloride Channel (1) Cholinesterase (ChE) (1) DNA/RNA Synthesis (4) Endogenous Metabolite (5) Estrogen Receptor/ERR (4) Glucosylceramide Synthase (GCS) (1) GnRH Receptor (1) HDAC (2) Isotope-Labeled Compounds (3) Melanocortin Receptor (2) Mitochondrial Metabolism (1) Nuclear Hormone Receptor 4A/NR4A (1) P2Y Receptor (1) Parasite (3) PERK (1) RAR/RXR (1) RET (1) TRP Channel (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (1) Endocrinology (5) Infection (7) Inflammation/Immunology (4) Metabolic Disease (10) Neurological Disease (6)

By Targets:

5-HT Receptor (2)

Androgen Receptor (1)

Bacterial (2)

Biochemical Assay Reagents (7)

Chloride Channel (1)

Cholinesterase (ChE) (1)

DNA/RNA Synthesis (4)

Endogenous Metabolite (5)

Estrogen Receptor/ERR (4)

Glucosylceramide Synthase (GCS) (1)

GnRH Receptor (1)

HDAC (2)

Isotope-Labeled Compounds (3)

Melanocortin Receptor (2)

Mitochondrial Metabolism (1)

Nuclear Hormone Receptor 4A/NR4A (1)

P2Y Receptor (1)

Parasite (3)

PERK (1)

RAR/RXR (1)

RET (1)

TRP Channel (1)

By Research Areas:

Cancer (13)

Cardiovascular Disease (1)

Endocrinology (5)

Infection (7)

Inflammation/Immunology (4)

Metabolic Disease (10)

Neurological Disease (6)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Amino Acid Derivatives Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0367

Maleic Acid

1 Publications Verification

Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes.

Maleic Acid 1 Publications Verification
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of *E. coli* and *L. monocytogenes*.

HY-Y1147

Diethyl maleate Maleic acid diethyl ester
Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells .

HY-Y0367S

Maleic Acid-d2 Maleic-2,3-d2 acid	Bacterial Endogenous Metabolite	Infection
Maleic Acid-d₂ is the deuterium labeled Maleic Acid[1]. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes[2][3].

HY-W127447

Maleate trihydrate sodium Maleic acid sodium	Biochemical Assay Reagents	Others
Maleic acid sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-59354R

Maleic hydrazide (Standard)	DNA/RNA Synthesis	Cancer
Maleic hydrazide (Standard) is the analytical standard of Maleic hydrazide. This product is intended for research and analytical applications. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins .

HY-59354

Maleic hydrazide	DNA/RNA Synthesis	Cancer
Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins .

HY-59354S

Maleic hydrazide-d2	DNA/RNA Synthesis	Cancer
Maleic hydrazide-d₂ is the deuterium labeled Maleic hydrazide[1]. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[2][3].

HY-15284B

*Prasugrel (Maleic* acid)** PCR 4099 (Maleic acid)	P2Y Receptor	Cardiovascular Disease
Prasugrel (PCR 4099) Maleic acid is a thienopyridine and proagent, inhibits platelet function. Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-W127723

*Fluoresceinamine maleic* acid monoamide**	Biochemical Assay Reagents	Others
Fluoresceinamine Maleic Acid Monoamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-20558

D-(+)-Malic acid D-Malic acid	Endogenous Metabolite	Metabolic Disease
D-(+)-Malic acid (D-Malic acid), an active enantiomer of Malic acid, is a competitive inhibitor of L(--)malic acid transport .

HY-Y1311S

Malic acid-d3 Hydroxybutanedioic acid-d₃; E 296-d₃	Endogenous Metabolite	Others
Malic acid-d₃ is the deuterium labeled Malic acid. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods[1][2].

HY-Y1069S3

(S)-Malic acid-13C4

(S)-Hydroxybutanedioic acid-¹³C₄; (S)-E 296-¹³C₄
Isotope-Labeled Compounds Others

(S)-Malic acid- ¹³C₄ is the ¹³C labeled S-Malic acid (HY-Y1069)[1].

(S)-Malic acid-13C4 (S)-Hydroxybutanedioic acid-¹³C₄; (S)-E 296-¹³C₄	Isotope-Labeled Compounds	Others
(S)-Malic acid- ¹³C₄ is the ¹³C labeled S-Malic acid (HY-Y1069)[1].

HY-128900

11-cis-Vaccenyl acetate	Endogenous Metabolite	Others
11-cis-Vaccenyl acetate is male-specific lipid that mediates aggregation behavior in both male and female flies, which activates a few dozen olfactory neurons located in T1 sensilla on the antenna of both male and female flies .

HY-Y1069S

(S)-Malic acid-d3 (S)-Hydroxybutanedioic acid-d₃; (S)-E 296-d₃	Endogenous Metabolite	Metabolic Disease
(S)-Malic acid-d₃ is the deuterium labeled (S)-Malic acid. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive[1][2].

HY-124861

Malic enzyme inhibitor ME1 2 Publications Verification ME1	Others	Metabolic Disease Cancer
Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC₅₀ of 0.15 μM .

HY-W250305

Calcium malate

Biochemical Assay Reagents Others

Calcium malate consists of calcium and malic acid.
HY-116047

Anisylacetone

p-Methoxybenzylacetone
Others Others

Anisylacetone (p-Methoxybenzylacetone) is a male fruit fly attractant .
HY-P5719

Andropin

Bacterial Infection

Andropin is a male-specific antibacterial peptide that can be found in Drosophila melanogaster .

Calcium malate	Biochemical Assay Reagents	Others
Calcium malate consists of calcium and malic acid.

Anisylacetone p-Methoxybenzylacetone	Others	Others
Anisylacetone (p-Methoxybenzylacetone) is a male fruit fly attractant .

Andropin	Bacterial	Infection
Andropin is a male-specific antibacterial peptide that can be found in Drosophila melanogaster .

HY-16743A

Ibiglustat (L-Malic acid) 2 Publications Verification Venglustat (L-Malic acid); SAR402671 (L-Malic acid); GZ402671 (L-Malic acid)	Glucosylceramide Synthase (GCS)	Metabolic Disease
Ibiglustat (Venglustat) L-Malic acid is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat L-Malic acid can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease .

HY-Y1311

Malic acid 1 Publications Verification Hydroxybutanedioic acid; E 296
Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods.

HY-18996

Adjudin 2 Publications Verification AF-2364	Chloride Channel Mitochondrial Metabolism	Cancer
Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin is also a potent Cl ^- channel blocker.

HY-150621

AS1134900

Others Cancer

AS1134900 is a highly selective, allosteric and uncompetitive NADP ⁺-dependent malic enzyme 1 (ME1) inhibitor .

AS1134900	Others	Cancer
AS1134900 is a highly selective, allosteric and uncompetitive NADP ⁺-dependent malic enzyme 1 (ME1) inhibitor .

HY-W780790

(Z,Z)-3,13-Octadecadienyl acetate	Others	Others
(Z,Z)-3,13-Octadecadienyl acetate is a compound that can be isolated from the pheromone gland extracts of female S. bicingulata moths. (Z,Z)-3,13-Octadecadienyl acetate is essential for attraction of male S. bicingulata moths. (Z,Z)-3,13-Octadecadienyl acetate can be used as bait to trap male moths .

HY-101812

Terbufibrol

Others Metabolic Disease

Terbufibrol has been shown highly active in reducing serum total cholesterol (TC) levels in the normal and hypercholesterolemic male rat.

Terbufibrol	Others	Metabolic Disease
Terbufibrol has been shown highly active in reducing serum total cholesterol (TC) levels in the normal and hypercholesterolemic male rat.

HY-W009688

Dibutyl maleate	Others	Inflammation/Immunology
Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice .

HY-W250303

Malic acid disodium salt Hydroxybutanedioic acid disodium salt; E 296 disodium salt	Biochemical Assay Reagents	Others
Sodium DL-Malate is an organic compound commonly used as a food additive, buffer and nutritional supplement. It contains sodium and malic acid. Malic acid disodium salt has several properties suitable for these applications, including the ability to enhance food flavor, improve texture and regulate acidity. Additionally, it can be used as a dietary supplement due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance.

HY-Y1069

(S)-Malic acid 1 Publications Verification (S)-Hydroxybutanedioic acid; (S)-E 296
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-N6976

Ascr#8

Others Infection

Ascr#8 is an dauer-inducing ascaroside isolated from Caenorhabditis elegans, synergizes with ascr#2 and ascr#3, and strongly enhances male attraction .
HY-W751152

α,β-Thujone

Others Cancer

α,β-Thujone is a component of the essential oils of some plants. α,β-Thujone causes cancers in male rats and induces seizures in the highest doses .

Ascr#8	Others	Infection
Ascr#8 is an dauer-inducing ascaroside isolated from Caenorhabditis elegans, synergizes with ascr#2 and ascr#3, and strongly enhances male attraction .

α,β-Thujone	Others	Cancer
α,β-Thujone is a component of the essential oils of some plants. α,β-Thujone causes cancers in male rats and induces seizures in the highest doses .

HY-N6977

Ascr#3	Others	Infection
Ascr#3 is an ascaroside isolated from Caenorhabditis elegans, acts a potent male attractant, and also promotes dauer formation combined with ascr#2 at low concentration .

HY-N6974

Ascr#2 Ascaroside C6	Others	Infection
Ascr#2 is an ascaroside isolated from Caenorhabditis elegans, potently promotes dauer formation, and also acts as a potent male attractant combined with ascr#3 at low concentration .

HY-W087952

(R)-(-)-2-Butanol	Others	Metabolic Disease
(R)-(-)-2-Butanol is released by the females of the white grub beetle, Dasylepida ishigakiensis, to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling .

HY-120989

Methyl 7(Z)-hexadecenoate	Others	Metabolic Disease
Methyl 7(Z)-hexadecenoate is a sex pheromone produced by Trogoderma glabrum. Methyl 7(Z)-hexadecenoate can elicit attractive and sexually excitatory responses in Trogoderma glabrum males .

HY-B0860

Diuron
Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male and female mice by 73 and 27%, respectively.

HY-32004

Coumalic acid	Biochemical Assay Reagents	Others
Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity .

HY-118861

Enclomiphene (E)-Clomiphene; trans-Clomiphene; Enclomifene	Estrogen Receptor/ERR	Metabolic Disease Endocrinology
Enclomiphene ((E)-Clomiphene) is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes .

HY-118861B

Enclomiphene hydrochloride (E)-Clomiphene hydrochloride; trans-Clomiphene hydrochloride; Enclomifene hydrochloride	Estrogen Receptor/ERR	Metabolic Disease Endocrinology
Enclomiphene ((E)-Clomiphene) hydrochloride is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene hydrochloride can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes .

HY-N8028

Quercetin 3-O-sambubioside 1 Publications Verification	Others	Cancer
Quercetin-3-O-sambubioside is a monomeric compound found in Eucommia ulmoides male flowers. Quercetin-3-O-sambubioside promotes the stimulation of the nerve center. Antioxidant and anticancer activities .

HY-119419S

Pirimicarb-d6	Cholinesterase (ChE) Parasite Isotope-Labeled Compounds	Others
Pirimicarb-d₆ is the deuterium labeled Diuron. Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male

HY-118861A

Enclomiphene citrate 1 Publications Verification (E)-Clomiphene citrate; trans-Clomiphene citrate; Enclomifene citrate	Estrogen Receptor/ERR	Metabolic Disease Endocrinology
Enclomiphene ((E)-Clomiphene) citrate is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene citrate can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes .

HY-119332

3-Keto petromyzonol	Others	Endocrinology
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey .

HY-148163

Polystyrene	Others	Others
Polystyrene can form Polystyrene microplastics (PS-MPs), a hazardous material with potential toxicity. Polystyrene microplastics is harm to zebrafish heart and induces male reproductive toxicity in mice . MCE provides Polystyrene products in solution packaging.

HY-156280

RARα antagonist 1

RAR/RXR Endocrinology

RARα antagonist 1 (compound 21) is an orally active and selective retinoic acid receptor α(RARα) antagonist, with the IC₅₀ of 4.6nM .

RARα antagonist 1	RAR/RXR	Endocrinology
RARα antagonist 1 (compound 21) is an orally active and selective retinoic acid receptor α(RARα) antagonist, with the IC₅₀ of 4.6nM .

HY-109517

Calf thymus DNA DNA from calf thymus, Thymonucleic acid	DNA/RNA Synthesis	Inflammation/Immunology Cancer
Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. Calf thymus DNA can be used for the research of the interaction between DNA and agents .

HY-115684

2-Undecanol Undecan-2-ol	Others	Others
2-Undecanol (Undecan-2-ol) is a male specific volatile identified from the sap beetle Lobiopa insularis. 2-undecanol is a flower emitted volatile, used by various species of Hymenoptera as a pheromone component .

HY-P5883

TAT-M2NX tatM2NX	TRP Channel	Neurological Disease
TAT-M2NX (tatM2NX) is a TRPM2 inhibitor with specific neuroprotective activity in male mice. TAT-M2NX can be used to study ischemic neuronal damage .

HY-110157

AC-186	Estrogen Receptor/ERR	Neurological Disease
AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC₅₀s of 6 nM and 5000 nM for ERβ and ERα, respectively. AC-186 shows gender selective neuroprotective effects in a male rat model of Parkinson's disease .

HY-N6996S

Methyl Eugenol-13C,d3	Isotope-Labeled Compounds	Others
Methyl Eugenol- ¹³C,d₃ is the ¹³C- and deuterium labeled Methyl Eugenol. Methyl Eugenol, a phenylpropanoid chemical in leaves, fruits, stems, and/or roots, may be released when that corresponding part of a plant is damaged as a result of feeding by an herbivore. Methyl Eugenol is used for male annihilation of the oriental fruit fly[1].

HY-D0843

N-Ethylmaleimide Maximum Cited Publications 10 Publications Verification NEM
N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC₅₀ value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .

HY-157429

25N-N1-Nap	5-HT Receptor	Neurological Disease
25N-N1-Nap (compound 16) is a β-arrestin-biased 5-HT2A agonist. 25N-N1-Nap antagonizes phencyclidine induced hyperactivity in Male C57BL/6?J mice .

Cat. No.	Product Name	Target	Research Area

HY-P1917A

Uty HY Peptide (246-254) (TFA)	Peptides	Inflammation/Immunology
Uty HY Peptide (246-254) TFA, derived from the ubiquitously transcribed tetratricopeptide repeat gene on the Y chromosome (UTY) protein as an H-Y epitope, H-YD ^b, is a male-specific transplantation antigen H-Y .

HY-P5719

Andropin

Bacterial Infection

Andropin is a male-specific antibacterial peptide that can be found in Drosophila melanogaster .

HY-139741

cyclo(Phe-Ala-Gly-Arg-Arg-Arg-Gly-AEEAc)	Peptides	Others
cyclo(Phe-Ala-Gly-Arg-Arg-Arg-Gly-AEEAc) provides an avenue for developing a nonhormonal male contraceptive by blocking of GRTH/DDX25 phosphorylation.

HY-P1917

Uty HY Peptide (246-254)	Peptides	Inflammation/Immunology
Uty HY Peptide (246-254), derived from the ubiquitously transcribed tetratricopeptide repeat gene on the Y chromosome (UTY) protein as an H-Y epitope, H-YD ^b, is a male-specific transplantation antigen H-Y .